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CD30 Antibody [mCD30.1]

CATALOG NUMBER: 76-018

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Hamster
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Hamster
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Armenian Hamster IgG
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
Tnfrsf8
Additional Names:
Ki, Cd30, Ki-1, D1S166E, Tnfrsf8
Ncbi Gene Id Number:
21941
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.
Background Reference 1:
Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2.Diabetes,49(9), 1612-1616.
Background Reference 2:
Falini, B., Pileri, S., Pizzolo, G., D, H., Flenghi, L., Stirpe, F., ... Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.BLOOD-NEW YORK-,85, 1-1.
Background Reference 3:
Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., Miller, J. F. (1999). CD 30 prevents Tcell responses to nonlymphoid tissues.Immunological reviews,169(1), 23-29.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-018

List Size:
0.5 mg

List Price:

$540.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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