CD309 Antibody [Avas12a1] (PE)

CATALOG NUMBER: 76-991

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The Avas12a1 monoclonal antibody specifically reacts with mouse CD309, also known as fetal liver kinase-1 (Flk-1) or the vascular endothelial growth factor receptor 2 (VEGFR2).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Kdr
Additional Names:
Flk1, Ly73, Flk-1, Krd-1, VEGFR2, VEGFR-2, sVEGFR-2, 6130401C07, Kdr
Ncbi Gene Id Number:
16542
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Avas12a1 monoclonal antibody specifically reacts with mouse CD309, also known as fetal liver kinase-1 (Flk-1) or the vascular endothelial growth factor receptor 2 (VEGFR2). CD309 is a receptor for VEGF and VEGFC and is expressed in endothelial cells in embryonic and adult tissue and a requirement for the development of vascular endothelial and hematopoietic cells.
Background Reference 1:
Kataoka, H., Takakura, N., Nishikawa, S., Tsuchida, K., Kodama, H., Kunisada, T., ... Nishikawa, S. I. (1997). Expressions of PDGF receptor alpha, cKit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells.Development, growth differentiation,39(6), 729-740.
Background Reference 2:
Ishitobi, H., Matsumoto, K., Azami, T., Itoh, F., Itoh, S., Takahashi, S., Ema, M. (2010). Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development.Experimental animals,59(5), 615-622.
Background Reference 3:
Yamashita, J., Itoh, H., Hirashima, M., Ogawa, M., Nishikawa, S., Yurugi, T., ... Nishikawa, S. I. (2000). Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors.Nature,408(6808), 92-96.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-991

List Size:
0.1 mg

List Price:

$391.00

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