CD309 Antibody [Avas12a1] (PE)

CATALOG NUMBER: 76-992

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The Avas12a1 monoclonal antibody specifically reacts with mouse CD309, also known as fetal liver kinase-1 (Flk-1) or the vascular endothelial growth factor receptor 2 (VEGFR2).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Kdr
Additional Names:
Flk1, Ly73, Flk-1, Krd-1, VEGFR2, VEGFR-2, sVEGFR-2, 6130401C07, Kdr
Ncbi Gene Id Number:
16542
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Avas12a1 monoclonal antibody specifically reacts with mouse CD309, also known as fetal liver kinase-1 (Flk-1) or the vascular endothelial growth factor receptor 2 (VEGFR2). CD309 is a receptor for VEGF and VEGFC and is expressed in endothelial cells in embryonic and adult tissue and a requirement for the development of vascular endothelial and hematopoietic cells.
Background Reference 1:
Sekine, C., Moriyama, Y., Koyanagi, A., Koyama, N., Ogata, H., Okumura, K., Yagita, H. (2009). Differential regulation of splenic CD8 dendritic cells and marginal zone B cells by Notch ligands.International immunology,21(3), 295-301.
Background Reference 2:
Yamaguchi, E., Chiba, S., Kumano, K., Kunisato, A., Takahashi, T., Takahashi, T., Hirai, H. (2002). Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice.Immunology letters,81(1), 59-64.
Background Reference 3:
Elyaman, W., Bradshaw, E. M., Wang, Y., Oukka, M., Kiviskk, P., Chiba, S., ... Khoury, S. J. (2007). JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis.The Journal of Immunology,179(9), 5990-5998.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-992

List Size:
0.2 mg

List Price:

$626.00

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