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CD31 Antibody [WM59]

CATALOG NUMBER: 76-160

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
PECAM1
Additional Names:
CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM, PECAM1
Ncbi Gene Id Number:
5175
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Background Reference 1:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 2:
Porat, Y., Porozov, S., Belkin, D., Shimoni, D., Fisher, Y., Belleli, A., ... Savion, N. (2006). Isolation of an adult bloodderived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.British journal of haematology,135(5), 703-714.
Background Reference 3:
Vaporciyan, A. A., DeLisser, H. M., Yan, H. C., Jones, M. L., Ward, P. A., Albelda, S. M. (1993). Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo.Science,262(5139), 1580-1582.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-160

List Size:
0.1 mg

List Price:

$419.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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