CD32 (phospho Tyr292) Antibody

CATALOG NUMBER: 79-796

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
CD32 (phospho Tyr292) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y (p)-S-L) derived from Human CD32.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292.
Predicted Molecular Weight:
32 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
FCGR2B
Additional Names:
CD32, FCG2, FCG2B,, LY-17, CDW32
Protein Accession Number:
NP_003992.3
Protein Gi Number:
50511930
Ncbi Gene Id Number:
2213
Background:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Background Reference 1:
Stuart S.G., EMBO J. 8:3657-3666(1989).
Background Reference 2:
Brooks D.G., J. Exp. Med. 170:1369-1385(1989).
Background Reference 3:
Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-796

List Size:
0.1 mg

List Price:

$376.00

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