CD33 Antibody [WM53] (FITC)

CATALOG NUMBER: 76-309

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
FITC
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CD33
Additional Names:
p67, SIGLEC3, SIGLEC-3, CD33
Ncbi Gene Id Number:
945
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67. CD33 is expressed on monocytes, granulocytes, dendritic cells, mast cells, and myeloid progenitors to the exclusion of hematopoietic stem cells, lymphocytes, and platelets. It functions to assist sialic acid-dependent cell adhesion.
Background Reference 1:
Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 2:
Favaloro, E. J., Bradstock, K. F., Kabral, A., Grimsley, P., Zowtyj, H., Zola, H. (1988). Further characterization of human myeloid antigens (gp160, 95; gp150; gp67): investigation of epitopic heterogeneity and nonhaemopoietic distribution using panels of monoclonal antibodies belonging to CD11b, CD13 and CD33.British journal of haematology,69(2), 163-171
Background Reference 3:
Freeman, S. D., Kelm, S., Barber, E. K., Crocker, P. R. (1995). Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.Blood,85(8), 2005-2012.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-309

List Size:
100 tests

List Price:

$365.00

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