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CD38 Antibody [90]

CATALOG NUMBER: 76-755

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Mouse IgG2a, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
Cd38
Additional Names:
ADPRC 1, Cd38-rs1, Cd38
Ncbi Gene Id Number:
12494
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Background Reference 1:
Gonzlez-lvaro, I., Domnguez-Jimnez, C., Ortiz, A. M., Nez-Gonzlez, V., Roda-Navarro, P., Fernndez-Ruiz, E., ... Snchez-Madrid, F. (2006). Interleukin-15 and interferon- gammaparticipate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production.Arthritis research therapy,8(4), R88.
Background Reference 2:
Katagiri, T., Qi, Z., Ohtake, S., Nakao, S. (2011). GPIanchored proteindeficient T cells in patients with aplastic anemia and lowrisk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure.European journal of haematology,86(3), 226-236.
Background Reference 3:
Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J., Thorley-Lawson, D. A. (1991). Expression of the Blast-1 activation/adhesion molecule and its identification as CD48.The Journal of immunology,146(7), 2192-2200.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-755

List Size:
0.5 mg

List Price:

$494.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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