CD38 Antibody [HIT2] (Violet-450)

CATALOG NUMBER: 76-748

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Violet-450
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Violet-450
Tested Applications:
Flow
Specificity:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CD38
Additional Names:
T10, ADPRC 1, CD38
Ncbi Gene Id Number:
952
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Background Reference 1:
Deaglio, S., Morra, M., Mallone, R., Ausiello, C. M., Prager, E., Garbarino, G., ... Malavasi, F. (1998). Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member.The Journal of Immunology,160(1), 395-402.
Background Reference 2:
McMichael, A. J. (1987).Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA.
Background Reference 3:
HORENSTEIN, A., STOCKINGER, H., Imhof, B., MALAVASI, F. (1998). CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J,330, 1129-1135.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-748

List Size:
100 tests

List Price:

$436.00

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