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CD4 Antibody [OKT4]

CATALOG NUMBER: 76-319

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays, ICC, IF, IP, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays, ICC, IF, IP, WB
Specificity:
The OKT4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG2b, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CD4
Additional Names:
CD4mut, CD4
Ncbi Gene Id Number:
920
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The OKT4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II). The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
Background Reference 1:
Reinherz, E. L., Kung, P. C., Goldstein, G., Schlossman, S. F. (1979). Separation of functional subsets of human T cells by a monoclonal antibody.Proceedings of the National Academy of Sciences,76(8), 4061-4065.
Background Reference 2:
Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 3:
Bour, S. T. E. P. H. A. N. E., Boulerice, F. R. A. N. C. O. I. S., Wainberg, M. A. (1991). Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.Journal of virology,65(12), 6387-6396.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-319

List Size:
0.1 mg

List Price:

$217.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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