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The purity of Cynomolgus CD4 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of Cynomolgus CD4 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

CD4 Recombinant Protein

CATALOG NUMBER: 96-106

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Rhesus monkey
source-species:
HEK293 cells
Recombinant Protein Sequence:
Lys 26 - Trp 390
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
42.3 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Additional Names:
CD4, CD4mut, LEU3
Protein Accession Number:
G7N5T8
Background:
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
Background Reference 1:
Brady RL, et al., 1993, Science 260 (5110): 979–83.
Background Reference 2:
Zeitlmann, L., et al., 2001, J. Biol. Chem. (United States) 276 (12): 9123–32.
Background Reference 3:
Rudd CE, et al., 2010, J. Immunol. 185 (5): 2645–9.
Background Reference 4:
Rudd CE, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (14): 5190–4.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-106

List Size:
0.1 mg

List Price:

$463.00

Datasheet
Shipping Info

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