Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

CD40 Antibody [HM40-3]

CATALOG NUMBER: 76-026

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Hamster
Species Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Hamster
Species Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Armenian Hamster IgM, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
Cd40
Additional Names:
IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, Cd40
Ncbi Gene Id Number:
21939
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Background Reference 1:
Kaneko, Y., Hirose, S., Abe, M., Yagita, H., Okumura, K., Shirai, T. (1996). CD40mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus.European journal of immunology,26(12), 3061-3065.
Background Reference 2:
Ferlin, W. G., Severinson, E., Strm, L., Heath, A. W., Coffman, R. L., Ferrick, D. A., Howard, M. C. (1996). CD40 signaling induces interleukin4independent IgE switching in vivo.European journal of immunology,26(12), 2911-2915.
Background Reference 3:
Kashiwada, M., Kaneko, Y., Yagita, H., Okumura, K., Takemori, T. (1996). Activation of mitogenactivated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells.European journal of immunology,26(7), 1451-1458.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-026

List Size:
0.5 mg

List Price:

$494.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369