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CD41 Antibody [MWReg30] (FITC)

CATALOG NUMBER: 76-173

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
FITC
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Itga2b
Additional Names:
CD41, CD41B, GpIIb, AI172977, alphaIIb, Itga2b
Ncbi Gene Id Number:
16399
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+,CD48-, and CD41- can be used to identify hematopoietic stem cells.
Background Reference 1:
Schmidt, R. E., Grau, G. E., M, D. N., Nieswandt, B., Echtenacher, B., Wachs, F. P., ... Gessner, J. E. (1999). Acute Systemic Reaction and Lung Alterations Induced by an Antiplatelet.Blood,94(2), 684-693.
Background Reference 2:
Bertrand, J. Y., Giroux, S., Golub, R., Klaine, M., Jalil, A., Boucontet, L., ... Cumano, A. (2005). Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin.Proceedings of the National Academy of Sciences of the United States of America,102(1), 134-139.
Background Reference 3:
Mitjavila-Garcia, M. T., Cailleret, M., Godin, I., Nogueira, M. M., Cohen-Solal, K., Schiavon, V., ... Vainchenker, W. (2002). Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells.Development,129(8), 2003-2013.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-173

List Size:
0.5 mg

List Price:

$494.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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