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CD48 Antibody [HM48-1]

CATALOG NUMBER: 76-760

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Hamster
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Hamster
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The HM48-1 monoclonal antibody specifically reacts with mouse CD48, a GPI-anchored molecule in the Ig superfamily.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Armenian Hamster IgG
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
Cd48
Additional Names:
BCM1, BLAST, Bcm-1, BLAST1, SLAMF2, Sgp-60, BLAST-1, MEM-102, AI449234, AW610730, Cd48
Ncbi Gene Id Number:
12506
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HM48-1 monoclonal antibody specifically reacts with mouse CD48, a GPI-anchored molecule in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells. The utilization of the HM48-1 antibody has been reported to prolong cardiac allografts survival in in vivo studies. The antibody blocks the interaction of CD2 and CD244, inhibits CTL priming, and blocks the binding of soluble CD2 to CD48 expressing cells.
Background Reference 1:
Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 2:
Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York
Background Reference 3:
McMichael, A. J., Beverley, P. C. L., Cobbold, S., Crumpton, M. J., Gilks, W., Gotch, F. M., ... Waldman, H. (1987). Leukocyte typing III.White Cell Differentiation Antigens, 733-786.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-760

List Size:
0.5 mg

List Price:

$519.00

Out of stock

Datasheet
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