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CD49f Antibody [4F10]

CATALOG NUMBER: 99-547

Clonality:
Monoclonal
Tested Applications:
Flow, IHC-Fr
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, IHC-Fr
Application Note:
CD49f Antibody [4F10] for use in flow cytometry, immunohistochemistry, and immunoprecipitation assays.
Specificity:
CD49f
Clonality:
Monoclonal
Isotype:
IgG2b
Physical State:
Liquid
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
ITGA6
Additional Names:
Integrin alpha6 chain, VLA-6 alpha chain, platelet gpIc
Protein Accession Number:
P23229
Ncbi Gene Id Number:
3655
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD49f is the 125 kDa integrin alpha6 chain which associates noncovalently with the integrin beta1 subunit (CD29) and with the integrin beta4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and alpha6beta4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes, and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes, and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-547

List Size:
0.1 mg

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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