CD51 Antibody [13C2]

CATALOG NUMBER: 99-550

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
African Green Monkey, Bovine, Human, Rabbit
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
African Green Monkey, Bovine, Human, Rabbit
Immunogen:
Cell suspension containing osteoclasts from osteoclastomas
Conjugate:
Unconjugated
Tested Applications:
Flow
Application Note:
CD51 Antibody [13C2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, purification, depletion, adhesion, and blocking assays.
Specificity:
CD51
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
ITGAV
Additional Names:
Integrin alphaV, vitronectin receptor, VNR-alpha chain
Protein Accession Number:
P06756
Ncbi Gene Id Number:
3685
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD51 represents the integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-550

List Size:
0.1 mg

List Price:

$275.00

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