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CD57 Antibody [TBO1]

CATALOG NUMBER: 76-634

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Mouse IgM
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
B3GAT1
Additional Names:
NK1, CD57, HNK1, LEU7, NK-1, GLCATP, GLCUATP, B3GAT1
Ncbi Gene Id Number:
27087
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle. It is reported that the molecule is involved in cell-matrix interactions and is upregulated in some disease states.
Background Reference 1:
Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005). Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175(12), 8415-8423.
Background Reference 2:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 3:
Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985). Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66(1), 64-68.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-634

List Size:
0.5 mg

List Price:

$540.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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