CD59 Antibody [OV9A2] (PE)

CATALOG NUMBER: 76-812

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The OV9A2 monoclonal antibody specifically reacts with human CD59 (Protectin), a 19-25 kDA GPI-anchored glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CD59
Additional Names:
1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20, CD59
Ncbi Gene Id Number:
966
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The OV9A2 monoclonal antibody specifically reacts with human CD59 (Protectin), a 19-25 kDA GPI-anchored glycoprotein. CD59 is expressed on hematopoietic and non-hematopoietic cells including lymphocytes, granulocytes, erythrocytes, monocytes and neurons. CD59 can inhibit complement cytolytic activity and the assembly of the membrane attack complex when bound to C8 and C9 complement components. It is involved in T cell activation and modulates T cell adhesion through interaction with CD2.
Background Reference 1:
Lu, H., Crawford, R. B., North, C. M., Kaplan, B. L., Kaminski, N. E. (2009). Establishment of an immunoglobulin m antibody-forming cell response model for characterizing immunotoxicity in primary human B cells.Toxicological sciences,112(2), 363-373.
Background Reference 2:
Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 3:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-812

List Size:
25 tests

List Price:

$253.00

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