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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the detected the CD68/CD68 (kpi) protein (arrow).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the detected the CD68/CD68 (kpi) protein (arrow).

CD68/CD68 Antibody

CATALOG NUMBER: 59-170

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CD68
Additional Names:
Macrosialin, Gp110, CD68, CD68
Protein Accession Number:
P34810
Protein Gi Number:
147744552
Ncbi Gene Id Number:
968
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a 110-kD transmembrane glycoprotein thatis highly expressed by human monocytes and tissue macrophages. Itis a member of the lysosomal/endosomal-associated membraneglycoprotein (LAMP) family. The protein primarily localizes tolysosomes and endosomes with a smaller fraction circulating to thecell surface. It is a type I integral membrane protein with aheavily glycosylated extracellular domain and binds to tissue- andorgan-specific lectins or selectins. The protein is also a memberof the scavenger receptor family. Scavenger receptors typicallyfunction to clear cellular debris, promote phagocytosis, andmediate the recruitment and activation of macrophages. Alternativesplicing results in multiple transcripts encoding differentisoforms.
Background Reference 1:
Leonarduzzi, G., et al. Mol Nutr Food Res 54 SUPPL 1, S31-S41 (2010) :
Background Reference 2:
Strojnik, T., et al. Anticancer Res. 29(8):3269-3279(2009)
Background Reference 3:
Sayed, S., et al. EurVasc Endovasc Surg 38(1):20-25(2009)
Background Reference 4:
Suzuki, Y., et al. IntRheum Dis 12(1):7-13(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-170

List Size:
400 ul

List Price:

$495.00

Datasheet
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