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CD86 Antibody [24F] (FITC)

CATALOG NUMBER: 76-606

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Rat
Conjugate:
FITC
Specifications
Host Species:
Mouse
Species Reactivity:
Rat
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Cd86
Additional Names:
B7-2, Cd86
Ncbi Gene Id Number:
56822
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions. The 24F antibody is capable of blocking the co-stimulatory activity of CD86.
Background Reference 1:
Maeda, K., Sato, T., Azuma, M., Yagita, H., Okumura, K. (1997). Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology,9(7), 993-1000.
Background Reference 2:
Damoiseaux, J. G., Yagita, H., Okumura, K., van Breda Vriesman, P. J. (1998). Costimulatory molecules CD80 and CD86 in the rat
Background Reference 3:
tissue distribution and expression by antigen-presenting cells.Journal of leukocyte biology,64(6), 803-809.
Background Reference 4:
BLUESTONE, J. (1995). New perspectives of CD28-B7-mediated T cell costimulation.Immunity,2, 555-559.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-606

List Size:
0.1 mg

List Price:

$365.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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