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CD8b Antibody [H35-17.2] (PE)

CATALOG NUMBER: 76-720

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2b, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Cd8b1
Additional Names:
Cd8b, Ly-3, Ly-C, Lyt-3, Cd8b1
Ncbi Gene Id Number:
12526
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.
Background Reference 1:
Driessens, M. H., Van Hulten, P., Zuurbier, A., La Riviere, G., Roos, E. (1996). Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18. Evidence that the LFA-1 binding sites for ICAM-1,-2, and-3 are distinct.Journal of leukocyte biology,60(6), 758-765.
Background Reference 2:
Zahalka, M. A., Naor, D. (1994). -beta-2-lntegrin dependent aggregate formation between LB T cell lymphoma and spleen cells: assessment of correlation with spleen invasiveness.International immunology,6(6), 917-924.
Background Reference 3:
Isobe, M., Yagita, H., Okumura, K., Ihara, A. (1992). Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1.Science,255(5048), 1125-1127.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-720

List Size:
0.05 mg

List Price:

$253.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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