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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

CD8B1 Antibody

CATALOG NUMBER: 56-141

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CD8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-167 amino acids from the C-terminal region of human CD8B1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
24 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CD8B
Additional Names:
T-cell surface glycoprotein CD8 beta chain, CD8b, CD8B, CD8B1
Protein Accession Number:
P10966
Protein Gi Number:
116032
Ncbi Gene Id Number:
926
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The CD8 antigen is a cell surface glycoprotein found onmost cytotoxic T lymphocytes that mediates efficient cell-cellinteractions within the immune system. The CD8 antigen, acting as acoreceptor, and the T-cell receptor on the T lymphocyte recognizeantigens displayed by an antigen presenting cell (APC) in thecontext of class I MHC molecules. The functional coreceptor iseither a homodimer composed of two alpha chains, or a heterodimercomposed of one alpha and one beta chain. Both alpha and betachains share significant homology to immunoglobulin variable lightchains. This gene encodes the CD8 beta chain isoforms. Multiplealternatively spliced transcript variants encoding distinctmembrane associated or secreted isoforms have been described. Apseudogene, also located on chromosome 2, has been identified.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Chen, M.L., et al. Eur. J. Immunol. 39(12):3423-3435(2009)
Background Reference 3:
Thakral, D., et al. J. Immunol. 180(11):7431-7442(2008)
Background Reference 4:
Stove, V., et al. J. Virol. 79(17):11422-11433(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-141

List Size:
400 ul

List Price:

$495.00

Datasheet
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