CDC14A Antibody

CATALOG NUMBER: 59-028

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CDC14A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human CDC14A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
67 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDC14A
Additional Names:
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Protein Accession Number:
Q9UNH5
Protein Gi Number:
55976620
Ncbi Gene Id Number:
8556
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the dualspecificity protein tyrosine phosphatase family. It is highlysimilar to Saccharomyces cerevisiae Cdc14, a protein tyrosinephosphatase involved in the exit of cell mitosis and initiation ofDNA replication, suggesting a role in cell cycle control. Thisprotein has been shown to interact with, and dephosphorylate tumorsuppressor protein p53, and is thought to regulate the function ofp53. Alternative splicing of this gene results in severaltranscript variants encoding distinct isoforms. [provided byRefSeq].
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 3:
Mocciaro, A., et al. J. Cell Biol. 189(4):631-639(2010)
Background Reference 4:
Song, S.Y., et al. APMIS 118(5):389-393(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-028

List Size:
400 ul

List Price:

$495.00

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