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Western blot analysis of anti-CDK1 Pab in A375 cell lysate
Western blot analysis of anti-CDK1 Pab in A375 cell lysate

CDC2 Antibody

CATALOG NUMBER: 62-963

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This CDC2 (CDK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CDC2 (CDK1).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDK1
Additional Names:
Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDK1, CDC2, CDC28A, CDKN1, P34CDC2
Protein Accession Number:
P06493
Protein Gi Number:
334302921
Ncbi Gene Id Number:
983
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Background Reference 1:
Chow, J.P., et al., J. Biol. Chem. 278(42):40815-40828 (2003).
Background Reference 2:
Nozoe, T., et al., J. Cancer Res. Clin. Oncol. 129(9):498-502 (2003).
Background Reference 3:
Margottin-Goguet, F., et al., Dev. Cell 4(6):813-826 (2003).
Background Reference 4:
Yuan, H., et al., J. Virol. 77(3):2063-2070 (2003).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-963

List Size:
400 ul

List Price:

$495.00

Datasheet
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