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CDC25C (phospho Ser198) Antibody

CATALOG NUMBER: 79-900

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
CDC25C (phospho Ser198) antibody was raised against a peptide sequence around phosphorylation site of Serine 198 (E-F-S (p)-L-K) derived from Human CDC25C.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of CDC25C only when phosphorylated at serine 198.
Predicted Molecular Weight:
53 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CDC25C
Additional Names:
CDC25M1, MPI1B, MPIP3, EC 3.1.3.48
Protein Accession Number:
NP_001274511.1
Protein Gi Number:
12408658
Ncbi Gene Id Number:
995
Background:
cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Background Reference 1:
Sadhu K., Proc. Natl. Acad. Sci. U.S.A. 87:5139-5143(1990).
Background Reference 2:
Bureik M., Int. J. Oncol. 17:1251-1258(2000).
Background Reference 3:
Wegener S., Eur. J. Cell Biol. 79:810-815(2000).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-900

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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