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Western blot: E coli-derived fusion protein as test antigen. XW-7097 dilution 1:2000. Colorimetric method for signal development. Predicted band size : 24 kDa
Western blot: E coli-derived fusion protein as test antigen. XW-7097 dilution 1:2000. Colorimetric method for signal development. Predicted band size : 24 kDa

CDC42 Antibody

CATALOG NUMBER: XW-7097

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
1-191
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
CDC42 antibody can be used for the detection of CDC42 by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
6.6 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
CDC42 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDC42
Additional Names:
Cell division control protein 42 homolog, G25K GTP-binding protein, G25K, CDC42Hs, CDC42
Protein Accession Number:
NP_001782.1
Protein Gi Number:
4757952
Ncbi Gene Id Number:
998
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Cell division cycle 42 isoform 1; cell division cycle 42 (GTP-binding protein, 25kD). This protein is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.
Background Reference 1:
Etienne-Manneville, S., Hall, A. Cdc42 regulates GSK-3-beta and adenomatous polyposis coli to control cell polarity. Nature 421: 753-756, 2003.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7097

List Size:
0.05 mg

List Price:

$535.00

Out of stock

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