CDCA4 Antibody

CATALOG NUMBER: 58-624

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CDCA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CDCA4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDCA4
Additional Names:
Cell division cycle-associated protein 4, Hematopoietic progenitor protein, CDCA4, HEPP
Protein Accession Number:
Q9BXL8
Protein Gi Number:
32699606
Ncbi Gene Id Number:
55038
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that belongs to the E2F familyof transcription factors. This protein regulates E2F-dependenttranscriptional activation and cell proliferation, mainly throughthe E2F/retinoblastoma protein pathway. It also functions in theregulaton of JUN oncogene expression. This protein showsdistinctive nuclear-mitotic apparatus distribution, it is involvedin spindle organization from prometaphase, and may also play a roleas a midzone factor involved in chromosome segregation orcytokinesis. Two alternatively spliced transcript variants encodingthe same protein have been noted for this gene. Two pseudogeneshave also been identified on chromosome 1.
Background Reference 1:
Tategu, M., et al. Biochimie 90(10):1515-1522(2008)
Background Reference 2:
Wang, L., et al. Cell Motil. Cytoskeleton 65(7):581-593(2008)
Background Reference 3:
Hayashi, R., et al. J. Biol. Chem. 281(47):35633-35648(2006)
Background Reference 4:
Walker, M.G. Curr Cancer Drug Targets 1(1):73-83(2001)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-624

List Size:
400 ul

List Price:

$495.00

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