CDCP1 Antibody

CATALOG NUMBER: 58-436

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CDCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-732 amino acids from the C-terminal region of human CDCP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
93 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDCP1
Additional Names:
CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, CDCP1, TRASK
Protein Accession Number:
Q9H5V8
Protein Gi Number:
317373455
Ncbi Gene Id Number:
64866
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CDCP1 is a transmembraneprotein containing three extracellular CUB domains. This protein isfound to be overexpressed in colon and lung cancers. Its expressionlevel is correlated with the metastatic ability of carcinoma cells.This protein is located on the cell surface. It has been shown tobe tyrosine phosphorylated in a cancer cell line. Alternativelyspliced transcript variants encoding distinct isoforms have beenreported.
Background Reference 1:
He, Y., et al. J. Biol. Chem. 285(34):26162-26173(2010)
Background Reference 2:
Miyazawa, Y., et al. Cancer Res. 70(12):5136-5146(2010)
Background Reference 3:
Mamat, S., et al. Oncol. Rep. 23(5):1221-1227(2010)
Background Reference 4:
Fukuchi, K., et al. Mol. Pharm. 7(1):245-253(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-436

List Size:
400 ul

List Price:

$495.00

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