CDH16 Antibody

CATALOG NUMBER: 57-241

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CDH16.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
90 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDH16
Additional Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Protein Accession Number:
O75309
Ncbi Gene Id Number:
1014
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the cadherin superfamily, genesencoding calcium-dependent, membrane-associated glycoproteins.Mapped to a previously identified cluster of cadherin genes onchromosome 16q22.1, the gene localizes with superfamily membersCDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of anextracellular domain containing 6 cadherin domains, a transmembraneregion and a truncated cytoplasmic domain but lacks the prosequenceand tripeptide HAV adhesion recognition sequence typical of mostclassical cadherins. Expression is exclusively in kidney, where theprotein functions as the principal mediator of homotypic cellularrecognition, playing a role in the morphogenic direction of tissuedevelopment.
Background Reference 1:
Thedieck, C., et al. J. Mol. Biol. 378(1):145-153(2008)
Background Reference 2:
Kuehn, A., et al. Am. J. Surg. Pathol. 31(10):1528-1533(2007)
Background Reference 3:
Thedieck, C., et al. Br. J. Cancer 92(11):2010-2017(2005)
Background Reference 4:
Hishikawa, K., et al. Biochem. Biophys. Res. Commun. 328(1):288-291(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-241

List Size:
400 ul

List Price:

$495.00

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