CDH19 Antibody

CATALOG NUMBER: 56-755

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CDH19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-640 amino acids from the C-terminal region of human CDH19.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
87 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDH19
Additional Names:
Cadherin-19, CDH19, CDH7L2
Protein Accession Number:
Q9H159
Protein Gi Number:
17366818
Ncbi Gene Id Number:
28513
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a type II classical cadherin from thecadherin superfamily and one of three cadherin 7-like genes locatedin a cluster on chromosome 18. The encoded membrane protein is acalcium dependent cell-cell adhesion glycoprotein comprised of fiveextracellular cadherin repeats, a transmembrane region and a highlyconserved cytoplasmic tail. Type II (atypical) cadherins aredefined based on their lack of a HAV cell adhesion recognitionsequence specific to type I cadherins. Since disturbance ofintracellular adhesion is a prerequisite for invasion andmetastasis of tumor cells, cadherins are considered primecandidates for tumor suppressor genes.
Background Reference 1:
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Background Reference 2:
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Background Reference 3:
Kools, P., et al. Genomics 68(3):283-295(2000)
Background Reference 4:
Shimoyama, Y., et al. Biochem. J. 349 (PT 1), 159-167 (2000) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-755

List Size:
400 ul

List Price:

$495.00

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