Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western Blot at 1:2000 dilution + NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis of CDKN2C using rabbit polyclonal CDKN2C Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CDKN2C gene.
CDKN2C Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western Blot at 1:2000 dilution + NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane.

CDKN2C Antibody

CATALOG NUMBER: 55-525

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This CDKN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-139 amino acids from the C-terminal region of human CDKN2C.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDKN2C
Additional Names:
Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
Protein Accession Number:
P42773
Protein Gi Number:
1168870
Ncbi Gene Id Number:
1031
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the INK4family of cyclin-dependent kinase inhibitors. This protein has beenshown to interact with CDK4 or CDK6, and prevent the activation ofthe CDK kinases, thus function as a cell growth regulator thatcontrols cell cycle G1 progression. Ectopic expression of this genewas shown to suppress the growth of human cells in a manner thatappears to correlate with the presence of a wild-type RB1 function.Studies in the knockout mice suggested the roles of this gene inregulating spermatogenesis, as well as in suppressingtumorigenesis. Two alternatively spliced transcript variants ofthis gene, which encode an identical protein, have been reported.
Background Reference 1:
Stratakis, C., et al. Clin. Genet. 78(5):457-463(2010)
Background Reference 2:
Cunningham, J.M., et al. Br. J. Cancer 101(8):1461-1468(2009)
Background Reference 3:
Eguchi, T., et al. Mol. Cancer Ther. 8(6):1460-1472(2009)
Background Reference 4:
Pei, X.H., et al. Cancer Cell 15(5):389-401(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-525

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369