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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

CDKN3 Antibody

CATALOG NUMBER: 60-846

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CDKN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human CDKN3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
24 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CDKN3
Additional Names:
Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase, CDKN3, CDI1, CIP2, KAP
Protein Accession Number:
Q16667
Protein Gi Number:
2499769
Ncbi Gene Id Number:
1033
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to the dualspecificity protein phosphatase family. It was identified as acyclin-dependent kinase inhibitor, and has been shown to interactwith, and dephosphorylate CDK2 kinase, thus prevent the activationof CDK2 kinase. This gene was reported to be deleted, mutated, oroverexpressed in several kinds of cancers. Alternatively splicedtranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 2:
Jiang, R., et al. Int. J. Cancer 126(5):1263-1274(2010)
Background Reference 3:
Okamoto, K., et al. Biochem. Biophys. Res. Commun. 351(1):216-222(2006)
Background Reference 4:
Hsieh, M.J., et al. Biochem. Biophys. Res. Commun. 349(2):573-581(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-846

List Size:
400 ul

List Price:

$495.00

Datasheet
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