CDMP-2 Recombinant Protein

CATALOG NUMBER: 40-202

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
Biological Activity:
The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC - 5 chondrogenic cells in the range of 2.0 - .0 μg/mL.
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized CDMP-2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CDMP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing CDMP-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
GDF6
Additional Names:
KFM, KFS, KFS1, KFSL, SGM1, BMP13, CDMP2, LCA17, MCOP4, SCDO4, MCOPCB6, GDF16GDF-6
Protein Accession Number:
NP_001001557.1
Protein Gi Number:
48475062
Ncbi Gene Id Number:
392255
Background:
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant human BMP-13/CDMP-2 is a 27.0kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-202

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $199.00 through $305.00

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