CEACAM3 Antibody

CATALOG NUMBER: 57-311

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CEACAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
27 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CEACAM3
Additional Names:
Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM3, CD66D, CGM1
Protein Accession Number:
P40198
Protein Gi Number:
218511974
Ncbi Gene Id Number:
1084
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the family ofcarcinoembryonic antigen-related cell adhesion molecules (CEACAMs),which are used by several bacterial pathogens to bind and invadehost cells. The encoded transmembrane protein directs phagocytosisof several bacterial species that is dependent on the small GTPaseRac. It is thought to serve an important role in controllinghuman-specific pathogens by the innate immune system. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Tsavaris, N., et al.Chemother 21(6):673-680(2009)
Background Reference 3:
Skubitz, K.M., et al.Transl Med 6, 78 (2008) :
Background Reference 4:
Stern-Ginossar, N., et al. J. Immunol. 179(7):4424-4434(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-311

List Size:
400 ul

List Price:

$495.00

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