Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis of CEACAM5 in rat lung tissue lysate with CEACAM5 antibody at (A) 1 and (B) 2 μg/ml.
Immunofluorescence of CEACAM5 in human lung tissue with CEACAM5 antibody at 20 μg/mL.
Western blot analysis of CEACAM5 in rat lung tissue lysate with CEACAM5 antibody at (A) 1 and (B) 2 μg/ml.
Trial Size

CEACAM5 Antibody

CATALOG NUMBER: 7453

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Rat
Immunogen:
CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5.
The immunogen is located within amino acids 310 - 360 of CEACAM5 .
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
CEACAM5 antibody can be used for detection of CEACAM5 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity:
CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.
Positive Control 1:
Cat. No. 1462 - Rat Lung Tissue Lysate
Positive Control 2:
Cat. No. 10-101 - Human Lung Tissue Slide
Predicted Molecular Weight:
Predicted: 77 kDa
Observed: 80kDa
Purification:
CEACAM5 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
CEACAM5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
CEACAM5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
CEACAM5
Additional Names:
CEACAM5 Antibody : CEA, CD66e, CEA, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen
Protein Accession Number:
NP_004354
Protein Gi Number:
98986445
Ncbi Gene Id Number:
1048
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).
Background Reference 1:
Gold P and Freedman SO. Specific carinoembryonic antigens of the human digestive system. J. Exp. Med. 1965; 122:467-81.
Background Reference 2:
Kuespert K, Pils S, and Hauck CR. CEACAMs: their role in physiology and pathophysiology. Curr. Opin. Cell Biol. 2006; 565-71.
Background Reference 3:
Yoshioka T, Masuko T, Kotanagi H, et al. Homotypic adhesion though carcinoembryonic antigen plays a role in hepatic metastasis development. Jpn. J. Cancer Res. 1998; 89:177-85.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7453

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369