CENPE Antibody

CATALOG NUMBER: 59-572

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CENPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2573-2601 amino acids from the C-terminal region of human CENPE.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
316 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CENPE
Additional Names:
Centromere-associated protein E, Centromere protein E, CENP-E, Kinesin-related protein CENPE, CENPE
Protein Accession Number:
Q02224
Protein Gi Number:
160358869
Ncbi Gene Id Number:
1062
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Centrosome-associated protein E is a kinesin-like motorprotein that accumulates in the G2 phase of the cell cycle. Unlikeother centrosome-associated proteins, it is not present duringinterphase and first appears at the centromere region ofchromosomes during prometaphase. CENPE is proposed to be one of themotors responsible for mammalian chromosome movement and/or spindleelongation.
Background Reference 1:
Kim, Y., et al. Cell 142(3):444-455(2010)
Background Reference 2:
Maia, A.F., et al. Chromosoma 119(4):405-413(2010)
Background Reference 3:
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Background Reference 4:
Maffini, S., et al. Curr. Biol. 19(18):1566-1572(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-572

List Size:
400 ul

List Price:

$495.00

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