CFD Antibody

CATALOG NUMBER: 56-222

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Immunogen:
This CFD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-99 amino acids from the N-terminal region of human CFD.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
27 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit IgG
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CFD
Additional Names:
Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD
Protein Accession Number:
P00746
Protein Gi Number:
158515408
Ncbi Gene Id Number:
1675
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thetrypsin family of peptidases. The encoded protein is a component ofthe alternative complement pathway best known for its role inhumoral suppression of infectious agents. This protein is also aserine protease that is secreted by adipocytes into thebloodstream. Finally, the encoded protein has a high level ofexpression in fat, suggesting a role for adipose tissue in immunesystem biology.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Hietaharju, A., et al. Eur. J. Neurol. 17(2):332-334(2010)
Background Reference 3:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 4:
Ciprandi, G., et al. Int. Immunopharmacol. 9(12):1460-1463(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-222

List Size:
400 ul

List Price:

$495.00

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