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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

CHD1L Antibody

CATALOG NUMBER: 58-475

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CHD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-590 amino acids from the Central region of human CHD1L.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
101 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CHD1L
Additional Names:
Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1, CHD1L, ALC1
Protein Accession Number:
Q86WJ1
Protein Gi Number:
311033359
Ncbi Gene Id Number:
9557
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
In response to DNA strand breaks, chromatin adopts arelaxed structure due to the addition of poly(ADP-ribose) (PAR) tochromatin proteins by PARP enzymes (see PARP1; MIM 173870), andthis relaxation facilitates the repair of DNA damage. CHD1Linteracts with PAR and has a role in chromatin relaxation followingDNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied byOMIM].
Background Reference 1:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 2:
Chen, L., et al. J. Clin. Invest. 120(4):1178-1191(2010)
Background Reference 3:
Ahel, D., et al. Science 325(5945):1240-1243(2009)
Background Reference 4:
Gottschalk, A.J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(33):13770-13774(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-475

List Size:
400 ul

List Price:

$495.00

Datasheet
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