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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

CHMP5 Antibody

CATALOG NUMBER: 59-959

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
25 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CHMP5
Additional Names:
Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, Vacuolar protein sorting-associated protein 60, Vps60, hVps60, CHMP5, C9orf83, SNF7DC2
Protein Accession Number:
Q9NZZ3
Protein Gi Number:
51702157
Ncbi Gene Id Number:
51510
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CHMP5 belongs to the chromatin-modifying protein/chargedmultivesicular body protein (CHMP) family. These proteins arecomponents of ESCRT-III (endosomal sorting complex required fortransport III), a complex involved in degradation of surfacereceptor proteins and formation of endocytic multivesicular bodies(MVBs). Some CHMPs have both nuclear and cytoplasmic/vesiculardistributions, and one such CHMP, CHMP1A (MIM 164010), is requiredfor both MVB formation and regulation of cell cycle progression(Tsang et al., 2006 [PubMed 16730941]).
Background Reference 1:
Wang, H.R., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16(2):282-285(2008)
Background Reference 2:
Row, P.E., et al. J. Biol. Chem. 282(42):30929-30937(2007)
Background Reference 3:
Huang, H.H., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15(4):738-742(2007)
Background Reference 4:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-959

List Size:
400 ul

List Price:

$495.00

Datasheet
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