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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

CHRNA5 Antibody

CATALOG NUMBER: 57-414

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This CHRNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human CHRNA5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CHRNA5
Additional Names:
Neuronal acetylcholine receptor subunit alpha-5, CHRNA5, NACHRA5
Protein Accession Number:
P30532
Protein Gi Number:
2506126
Ncbi Gene Id Number:
1138
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a nicotinicacetylcholine receptor subunit and a member of a superfamily ofligand-gated ion channels that mediate fast signal transmission atsynapses. These receptors are thought to be heteropentamerscomposed of separate but similar subunits. Defects in this genehave been linked to susceptibility to lung cancer type 2 (LNCR2).
Background Reference 1:
Wessel, J., et al. Neuropsychopharmacology 35(12):2392-2402(2010)
Background Reference 2:
Erlich, P.M., et al. Hum. Genet. 128(5):491-499(2010)
Background Reference 3:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 4:
Falvella, F.S., et al. J. Natl. Cancer Inst. 102(17):1366-1370(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-414

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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