Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

CHRNG Antibody

CATALOG NUMBER: 58-950

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CHRNG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human CHRNG.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CHRNG
Additional Names:
Acetylcholine receptor subunit gamma, CHRNG, ACHRG
Protein Accession Number:
P07510
Protein Gi Number:
126302510
Ncbi Gene Id Number:
1146
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The mammalian muscle-type acetylcholine receptor is atransmembrane pentameric glycoprotein with two alpha subunits, onebeta, one delta, and one epsilon (in adult skeletal muscle) orgamma (in fetal and denervated muscle) subunit. This gene, whichencodes the gamma subunit, is expressed prior to the thirty-thirdweek of gestation in humans. The gamma subunit of the acetylcholinereceptor plays a role in neuromuscular organogenesis and ligandbinding and disruption of gamma subunit expression prevents thecorrect localization of the receptor in cell membranes. Mutationsin this gene cause Escobar syndrome and a lethal form of multiplepterygium syndrome. Muscle-type acetylcholine receptor is the majorantigen in the autoimmune disease myasthenia gravis.
Background Reference 1:
Saccone, N.L., et al. Genes Brain Behav. (2010) In press :
Background Reference 2:
Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
Background Reference 3:
Saccone, N.L., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (4), 453-466 (2009) :
Background Reference 4:
Zouridakis, M., et al. Biochim. Biophys. Acta 1794(2):355-366(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-950

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369