CHST5 Antibody

CATALOG NUMBER: 60-215

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CHST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human CHST5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
46 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CHST5
Additional Names:
Carbohydrate sulfotransferase 5, 282-, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha, GST4-alpha, Intestinal N-acetylglucosamine-6-O-sulfotransferase, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, hIGn6ST, N-acetylglucosamine 6-O-sulfotransferase 3, GlcNAc6ST-3, Gn6st-3, CHST5
Protein Accession Number:
Q9GZS9
Protein Gi Number:
239938912
Ncbi Gene Id Number:
23563
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The carbohydrates of glycoconjugates are highly diversestructures with variation in monosaccharide composition, glycosidiclinkage positions, and branching of chains. Further diversity isadded by the covalent addition of sulfate moieties to particularhydroxyl groups and amino groups of saccharides. The sulfatemodifications of glycoproteins can be extensive in amount andfrequently occur at high density. They can have a profound effecton the physiochemical properties of the glycoconjugates, at leastin part through the addition of negative charge. Carbohydratesulfation plays a critical role in many biologic processes. CHST5belongs to the GST family of sulfotransferases, which also includesCHST1 (MIM 603797), CHST2 (MIM 603798), CHST3 (MIM 603799), andLSST. These enzymes are 6-O-sulfotransferases, which add sulfate toC6 of galactose (Gal), N-acetylgalactosamine (GalNAc), orN-acetylglucosamine (GlcNAc) (Lee et al., 1999 [PubMed10491328]).
Background Reference 1:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 2:
Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
Background Reference 3:
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Background Reference 4:
Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-215

List Size:
400 ul

List Price:

$495.00

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