CIAO1 Antibody

CATALOG NUMBER: 57-585

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This CIAO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the Central region of human CIAO1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CIAO1
Additional Names:
Probable cytosolic iron-sulfur protein assembly protein CIAO1 {ECO:0000255, HAMAP-Rule:MF_03037}, WD repeat-containing protein 39 {ECO:0000255, HAMAP-Rule:MF_03037}, CIAO1 {ECO:0000255, HAMAP-Rule:MF_03037}, WDR39
Protein Accession Number:
O76071
Ncbi Gene Id Number:
9391
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CIAO1 is an essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1.
Background Reference 1:
Srinivasan, V., et al. Structure 15(10):1246-1257(2007)
Background Reference 2:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 3:
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
Background Reference 4:
Johnstone, R.W., et al. J. Biol. Chem. 273(18):10880-10887(1998)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-585

List Size:
400 ul

List Price:

$495.00

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