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Western blot analysis in THP-1 cell line,human placenta,rat heart and skeletal muscle lysates (35ug/lane).
Western blot analysis in THP-1 cell line,human placenta,rat heart and skeletal muscle lysates (35ug/lane).

CIR Antibody

CATALOG NUMBER: 57-539

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human CIR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
52 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CIR1
Additional Names:
Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR
Protein Accession Number:
Q86X95
Protein Gi Number:
74727790
Ncbi Gene Id Number:
9541
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.
Background Reference 1:
Olsen,J.V., Cell 127 (3), 635-648 (2006)
Background Reference 2:
Maita,H., Exp. Cell Res. 303 (2), 375-387 (2005)
Background Reference 3:
Zhou,S., Mol. Cell. Biol. 21 (18), 6222-6232 (2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-539

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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