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Claudin 5 (phospho Tyr217) Antibody

CATALOG NUMBER: 79-902

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Claudin 5 (phospho Tyr217) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y (p)-V) derived from Human Claudin 5.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of Claudin 5 only when phosphorylated at tyrosine 217.
Predicted Molecular Weight:
23 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CLDN5
Additional Names:
CLD5, CLDN5, TMDVCF
Protein Accession Number:
NP_001124333.1
Protein Gi Number:
6685271
Ncbi Gene Id Number:
7122
Background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.
Background Reference 1:
Sirotkin H., Genomics 42:245-251(1997).
Background Reference 2:
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).
Background Reference 3:
The MGC Project Team; Genome Res. 14:2121-2127(2004).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-902

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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