CLC Antibody

CATALOG NUMBER: 57-733

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the C-terminal region of human CLC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
16 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CLC
Additional Names:
Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A
Protein Accession Number:
Q05315
Protein Gi Number:
317373429
Ncbi Gene Id Number:
1178
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Lysophospholipases are enzymes that act on biologicalmembranes to regulate the multifunctional lysophospholipids. Theprotein encoded by this gene is a lysophospholipase expressed ineosinophils and basophils. It hydrolyzes lysophosphatidylcholine toglycerophosphocholine and a free fatty acid. This protein maypossess carbohydrate or IgE-binding activities. It is bothstructurally and functionally related to the galectin family ofbeta-galactoside binding proteins. It may be associated withinflammation and some myeloid leukemias.
Background Reference 1:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 2:
Bryborn, M., et al. Allergy 65(2):220-228(2010)
Background Reference 3:
De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :
Background Reference 4:
Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106(24):9731-9736(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-733

List Size:
400 ul

List Price:

$495.00

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