CLCNKA Antibody

CATALOG NUMBER: 28-247

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLCNKA.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
CLCNKA antibody can be used for detection of CLCNKA by ELISA at 1:62500. CLCNKA antibody can be used for detection of CLCNKA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Predicted Molecular Weight:
75 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store CLCNKA antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
CLCNKA
Additional Names:
CLCNKA, CLCK1, ClC-K1, MGC61490, hClC-Ka
Protein Accession Number:
NP_004061
Protein Gi Number:
112382220
Ncbi Gene Id Number:
1187
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Background Reference 1:
Kramer, B.K., (2008) Nat Clin Pract Nephrol 4 (1), 38-46.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-247

List Size:
100 ul

List Price:

$519.00

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