CLCNKA Antibody

CATALOG NUMBER: 59-194

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CLCNKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CLCNKA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
75 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CLCNKA
Additional Names:
Chloride channel protein ClC-Ka, Chloride channel Ka, ClC-K1, CLCNKA
Protein Accession Number:
P51800
Protein Gi Number:
1705857
Ncbi Gene Id Number:
1187
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the CLC family of voltage-gatedchloride channels. The encoded protein is predicted to have 12transmembrane domains, and requires a beta subunit called barttinto form a functional channel. It is thought to function in saltreabsorption in the kidney and potassium recycling in the innerear. The gene is highly similar to CLCNKB, which is located 10 kbdownstream from this gene. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Kramer, B.K., et al. Nat Clin Pract Nephrol 4(1):38-46(2008)
Background Reference 4:
Martinez, G.Q., et al. PLoS ONE(7), E2746 (2008) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-194

List Size:
400 ul

List Price:

$495.00

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