CLN6 Antibody

CATALOG NUMBER: 26-214

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLN6.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
CLN6 antibody can be used for detection of CLN6 by ELISA at 1:1562500. CLN6 antibody can be used for detection of CLN6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
293T Cell Lysate
Predicted Molecular Weight:
36 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store CLN6 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
CLN6
Additional Names:
CLN6, FLJ20561, HsT18960, nclf, CLN4A
Protein Accession Number:
NP_060352
Protein Gi Number:
8923532
Ncbi Gene Id Number:
54982
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Background Reference 1:
Heine, C., (2007) Mol. Membr. Biol. 24 (1), 74-87.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

26-214

List Size:
100 ul

List Price:

$519.00

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