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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in HL-60 cell line lysates (35ug/lane).

CLN8 Antibody

CATALOG NUMBER: 60-084

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CLN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-280 amino acids from the C-terminal region of human CLN8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CLN8
Additional Names:
Protein CLN8, CLN8, C8orf61
Protein Accession Number:
Q9UBY8
Protein Gi Number:
145559455
Ncbi Gene Id Number:
2055
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a transmembrane protein belonging to afamily of proteins containing TLC domains, which are postulated tofunction in lipid synthesis, transport, or sensing. The proteinlocalizes to the endoplasmic reticulum (ER), and may recyclebetween the ER and ER-Golgi intermediate compartment. Mutations inthis gene are associated with progressive epilepsy with mentalretardation (EMPR), which is a subtype of neuronal ceroidlipofuscinoses (NCL). Patients with mutations in this gene havealtered levels of sphingolipid and phospholipids in the brain.
Background Reference 1:
Reinhardt, K., et al. Clin. Genet. 77(1):79-85(2010)
Background Reference 2:
Vantaggiato, C., et al. Hum. Mutat. 30(7):1104-1116(2009)
Background Reference 3:
Kousi, M., et al. Brain 132 (PT 3), 810-819 (2009) :
Background Reference 4:
Striano, P., et al. Epilepsy Behav 10(1):187-191(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-084

List Size:
400 ul

List Price:

$495.00

Datasheet
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