CNDP dipeptidase 2 Recombinant Protein

CATALOG NUMBER: 92-416

Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Met1-Asn475
Fusion Tag:
C-6 His tag
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Predicted Molecular Weight:
53.8 kD
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
physical-state:
Liquid
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl,10% Glycerol, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Storage Conditions:
Store at -20°C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Ncbi Official Symbol:
Cndp2
Additional Names:
CNDP2/CNDP dipeptidase 2/Cytosolic non-specific dipeptidase/Glutamate carboxypeptidase-like protein 1/Cn2, CNDP2, CPGL
Protein Accession Number:
Q9D1A2
Ncbi Gene Id Number:
66054
Background:
Mouse cytosolic non-specific dipeptidase(CNDP2) is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 has 2 Isoform: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 hydrolyzes a variety of dipeptides including L-carnosine and has a strong preference for Cys-Gly. It is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. It may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

92-416

List Size:
0.05 mg

List Price:

$515.00

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